Stroma composition and proliferative activity are related to therapy response in neoadjuvant treated pancreatic ductal adenocarcinoma.

Lena Haeberle,Andrea Cacciato Insilla,Anne-Christine Kapp,Katja Steiger,Anna Melissa Schlitter,Bjoern Konukiewitz,Ihsan Ekin Demir,Helmut Friess,Irene Esposito

Histology and histopathology（2021）

引用 8|浏览6

暂无评分

摘要

Similar to the stroma in therapy-naïve PDAC, the stroma of PDAC after NAT is heterogeneous. Distinguishing between desmoplastic stroma and therapy-induced fibrosis by single markers is not possible. Movat's pentachrome stain, IH for Ki-67, and to some extent for Tenascin C and alpha-SMA, can help detect poor histopathological response to NAT.

查看译文

关键词

Movat's stain,Neoadjuvant therapy,Pancreatic cancer,Proliferation,Stroma,Tumor regression grading

AI 理解论文

溯源树

样例

生成溯源树，研究论文发展脉络

Chat Paper

正在生成论文摘要