Hyperhomocysteinemia alters cytokine gene expression, cytochrome c oxidase activity and oxidative stress in striatum and cerebellum of rodents

•Chronic (30 days) mild HHCY induces oxidative stress in striatum and cerebellum.•Mild HHCY impairs cytochrome c oxidase and cholinergic system in the striatum and cerebellum.•Mild HHCY changes TNF-α and IL-1β gene expression in the striatum.•Mild HHCY changes TNF-α, IL-1β, IL-10 and TGF- β gene expression in the cerebellum.•Mild HHCY did not impair motor function in male rats.