A non-coding cancer mutation disrupting an HNF4α binding motif affects an enhancer regulating genes associated to the progression of liver cancer.

M Cavalli,K Diamanti,G Pan,M J Dabrowski,J Komorowski,C Wadelius

Experimental oncology（2021）

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摘要

The study highlights the importance of non-coding somatic mutations, vastly understudied, but likely to contribute to cancer development and progression.

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关键词

enhancer regulating genes,cancer,non-coding

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