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A review of combination adjuvants for malaria vaccines: a promising approach for vaccine development

International Journal for Parasitology(2021)

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摘要
•Subunit malaria vaccines fail to induce strong and long-lasting immune responses.•Adjuvants are essential for generating stronger and protective subunit vaccines.•No single adjuvant is capable of eliciting protective immunity in a malaria vaccine.•Combination adjuvants are a potent approach to improvemalaria vaccine efficacy.•This review outlines the status of combination adjuvants in malaria subunit vaccines.
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关键词
Combination adjuvants,Adjuvant system,Malaria,Plasmodium,Subunit vaccine,Immune response
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