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A new steroidal saponin from the aerial parts of Solanum torvum

NATURAL PRODUCT RESEARCH(2022)

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摘要
A new steroidal saponin, torvoside R (1), was isolated along with torvoside Q (2) and macaoside (3) from dichloromethane soluble-portion of the aerial parts of Solanum torvum. Their chemical structures were elucidated using HRESIMS, 1 D- and 2 D-NMR as well as comparison with those reported in the literature. All isolated compounds (1 - 3) exhibited cytotoxicity against SK-LU-1, HepG2, MCF-7, and T24 cancer cell lines with IC50 values ranging from 14.18 to 89.31 mu g/mL.
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关键词
Solanum torvum, steroidal saponin, cytotoxic activity
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