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Ccr5 Delta 32 Mutation And Gene Expression To Predict Outcome In Patients (Pts) With Metastatic Colorectal Cancer (Mcrc): Data From Fire-3 And Mavericc Phase Iii Trials

Annika Lenz,Wu Zhang,Yi Xiao,Joshua Millstein,Shivani Soni,Hiroyuki Arai,Jingyuan Wang,Aparna Raj Parikh,Christoph Mancao,Sebastian Stintzing,Volker Heinemann,Francesca Battaglin

Journal of Clinical Oncology（2020）

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Abstract
170Background: Germline polymorphisms in CCR5 have been associated with treatment outcome in pts with mCRC receiving regorafenib and cetuximab-based treatment. CCR5 Δ32, a loss of function deletion...
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Key words
metastatic colorectal cancer,colorectal cancer,gene expression,mcrc
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