REGOMUNE: A phase II study of regorafenib plus avelumab in solid tumors-Results of the non-MSI-H metastatic colorectal cancer (mCRC) cohort.

Sophie Cousin,Carine A. Bellera,Jean Philippe Guegan,Carlos A. Gomez-Roca,Jean-Philippe Metges,Antoine Adenis,Simon Pernot,Coralie Cantarel,Michele Kind,Maud Toulmonde,Kevin Bourcier,Isabelle Soubeyran,Alban Bessede,Antoine Italiano

JOURNAL OF CLINICAL ONCOLOGY（2020）

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摘要

4019Background: Regorafenib (R) has been shown to modulate anti-tumor immunity by different mechanisms including reduction of tumor-associated macrophages (TAMs). Synergy between R and anti–PD-1/PD...

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关键词

metastatic colorectal cancer,colorectal cancer,regorafenib,solid tumors—results,non-msi-h

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