High-performance liquid chromatographic evaluation of strong cation exchanger-based chiral stationary phases focusing on stationary phase characteristics and mobile phase effects employing enantiomers of tetrahydro-ß-carboline and 1,2,3,4-tetrahydroisoquinoline analogs

•Enantioselectivity of selectors based on strong cation exchangers are evaluated•Enantioseparation of pharmaceutically important cationic compounds is demonstrated•Structure-retention relationships are qualitatively discussed•The stoichiometric displacement model is applied for the description of the retention