The antimicrobial peptide TAT-RasGAP317-326 inhibits the formation and expansion of bacterial biofilms in vitro

•The novel antimicrobial peptide TAT-RasGAP317-326 potently inhibits biofilm formation by A. baumannii and P. aeruginosa.•TAT-RasGAP317-326 is more effective in biofilm eradication than classical antibiotics.•TAT-RasGAP317-326 also reduces biofilm formation by S. aureus.