Cardiovascular Dysfunction Risk in Young Adults with Congenital Adrenal Hyperplasia Caused by 21‐hydroxylase Enzyme Deficiency
International journal of clinical practice(2021)
Abstract
The association of congenital adrenal hyperplasia (CAH) caused by 21‐hydroxylase enzyme (21OHase) deficiency, duration of treatment and dosage with cardiovascular dysfunction in young adults remains unclear. We aimed to evaluate myocardial function, vascular structures and epicardial fat thickness in young adults with CAH as a result of 21OHase deficiency. Correlations between the duration and dose of glucocorticoid therapy and cardiovascular parameters were analysed.
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