New aromatic polyketides from the marine-derived fungus Pseudopithomyces maydicus PSU-AMF350 and their antimicrobial activity.

Four new aromatic polyketides including two diphenyl ethers (pseudopithoethers A-B, -), one benzofuranone (pseudopithonone, ) and one xanthone (pseudopithoxanthone, ), along with two known compounds (-) and one new naturally occurring hydroquinone (α,2,5-trihydroxyacetophenone, ) were isolated from the marine-derived fungus PSU-AMF350. Their structures were identified by analysis of spectroscopic data. All isolated compounds were tested for antimicrobial activity. Only compound displayed antibacterial activity against methicillin-resistant with the MIC value of 128 g/mL and against , NPRC005 and NPRC007 with the same MIC value of 200 g/mL.[Formula: see text].