Assembly of Polycyclic N-heterocycles Via Copper-Catalyzed Cycloamination of Indolylquinones and Aromatic Amines
Organic & biomolecular chemistry(2021)
摘要
The copper-catalyzed cycloamination of indolylquinones and various (hetero)aromatic amines under ligand-free conditions for the synthesis of polycyclic N-heterocycles has been developed. This method allows facile access to polycyclic N-heterocycles with the tolerance of chloride, bromide, amino, thio, etc. groups in moderate to high yields (60-89%).
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