Intestinal expression of ACE2 in mice with high-fat diet–induced obesity and neonates exposed to maternal high-fat diet

Nutrition(2021)

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摘要
•Intestinal ACE2 protein levels are increased in mice with high-fat diet-induced obesity.•Ace2 mRNA could be detected in intestinal macrophages but not in microglia.•Maternal high-fat diet feeding decreases intestinal ACE2 levels in the offspring compared with normal diet feeding.•Intestinal ACE2 protein levels are higher in neonates compared with adult and aging mice.
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关键词
ACE2,Intestine,High-fat diet,Macrophage,COVID-19
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