Design of experiments (DoE) to develop and to optimize nanoparticles as drug delivery systems

Luiz Marcela Tavares,Viegas Juliana Santos Rosa,Abriata Juliana Palma,Viegas Felipe,Vicentini Fabiana Testa Moura de Carvalho,Bentley Maria Vitória Lopes Badra,Chorilli Marlus,Marchetti Juliana Maldonado,Tapia-Blácido Delia Rita

European Journal of Pharmaceutics and Biopharmaceutics（2021）

引用 41|浏览12

暂无评分

摘要

•A survey of the principal DoE methods exploited in nanomedicine.•Overview of methods and composition that may affect nanomedicines particles.•To discuss how DoE can be exploited to optimize nanoparticles.•To present study cases that exploit the DoE strategies in nanomedicines.

查看译文

关键词

Box-Behnken Design,Central Composite Design,Full Factorial Design,Fractional Factorial Design,Nanomedicine,Nanotechnology,Plackett-Burman Design,Response Surface Methodology,Quality by Design

AI 理解论文

溯源树

样例

生成溯源树，研究论文发展脉络

Chat Paper

正在生成论文摘要