Effect of neuropsychiatric medications on mitochondrial function: For better or for worse

Tim L. Emmerzaal, Gerben Nijkamp,Marin Veldic,Shamima Rahman,Ana Cristina Andreazza,Eva Morava,Richard J. Rodenburg,Tamas Kozicz

Neuroscience & Biobehavioral Reviews（2021）

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摘要

•Antidepressants and other neuropsychiatric medications differentially influence mitochondrial function.•Specific antidepressants and other neuropsychiatric medications have negative effects on mitochondria.•Most antidepressants and other neuropsychiatric medications showed positive or mixed effects on mitochondrial function.

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关键词

Mitochondria,Electron transport chain complex proteins,Antidepressive agents,Drugs,In vivo studies

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