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Impact of hormonal biomarkers on response to hormonal therapy in advanced and recurrent endometrial cancer

Willem Jan VAN Weelden,Roy I Lalisang,Johan Bulten,Kristina Lindemann,Heleen J VAN Beekhuizen,Hans Trum,Dorry Boll,Henrica M J Werner,Luc R C W VAN Lonkhuijzen,Refika Yigit,David Forsse,Petronella O Witteveen,Khadra Galaal,Alexandra VAN Ginkel,Eliana Bignotti,Vit Weinberger,Sanne Sweegers,Judith R Kroep,Silvia Cabrera,Marc P L M Snijders,Márcia A Inda,Ane Gerda Z Eriksson,Camilla Krakstad,Andrea Romano,Anja VAN DE Stolpe,Johanna M A Pijnenborg

American Journal of Obstetrics and Gynecology（2021）

引用 9|浏览4
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摘要
Prediction of response to hormonal treatment in endometrial cancer improves substantially with a 50% cut-off level for PR-IHC and by applying a sequential test algorithm using PR-IHC and ER pathway activity scores. Results need to be validated in the PROMOTE-prospective study.
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关键词
aromatase inhibitors,estrogen receptor pathway activity,progesterone receptor,progestin therapy
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