Effective Sers Materials By Loading Ag Nanoparticles Into Poly(Acrylic Acid-Stat-Acrylamide)-Block-Polystyrene Nano-Objects Prepared By Pisa

Spherical nano-objects composed of poly(acrylic acid-stat-acrylamide)-block-polystyrene (P(AA-stat-Am)-b-PS) were prepared via polymerization induced self-assembly (PISA) and used as templates for the synthesis of hybrid Ag@P(AA-stat-Am)-b-PS. These well-defined hybrids were used as effective surface-enhanced Raman spectroscopy (SERS) supports for adenine detection as targeting molecule. Due to the presence of acrylamide units, the interactions between carboxyl groups, -COOH and AgNP were tuned, leading to the improvement of SERS effect in comparison to the system based on PAA-b-PS. SERS activity for Ag@P(AA(56)-stat-Am-19)-b-PS375 (ratio 1:1) was similar to 20 times higher (36x10(4)) as compared to the reference system; PAA(86)-b-PSt(380).