Pro-Tmune, The Next Generation Graft For Allogeneic Hematopoietic Cell Transplantation: Phase 1 Safety And Efficacy Data
BLOOD(2017)
摘要
ProTmune, an ex vivo modulated mobilized peripheral blood (mPB) graft, has FDA fast track designation for the reduction of incidence and severity of acute graft-versus-host disease (GvHD) in patients undergoing allogeneic hematopoietic cell transplantation (HCT). Despite the use of standard protocols to prevent its occurrence, 50 to 60% of patients receiving an unrelated allogeneic HCT experience acute GvHD within 60 days post-HCT.
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