Auditory Cortex Attentional Gain Modulation Is Impaired In First-Episode Psychosis

Selective attention is impaired at the first episode of psychosis (FEP). EEG and MEG can measure selective attention during an auditory oddball task, as N1 amplitude increases with attention. We previously reported N100-enhancement measured with EEG is reduced in FEP. Here, we source-resolved the concurrently recorded MEG activity and examined source activity within auditory cortex as a function of attention to sounds.