Genes, Early Life Stress, Brains, and Cognition: A Moderated Mediation Analysis

Heehwan Wang,Seo-Yoon Moon,Yoonjung Yoonie Joo,Eunji Lee,Jiook Cha

Biological psychiatry（2021）

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摘要

Genetic, environmental factors underlie brain and cognitive development in children. Testing the moderating effect of Early Life Stress (ELS) on gene-brain-cognition relationships is essential to understanding individual differences in cognitive development.

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关键词

Early Life Stress,Polygenic Risk Score (PRS),Brain Morphometry,Principal Components Analysis,Moderated Mediation Analysis

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