Late vascular complications after cranial radiotherapy: A report of two illustrative cases

Cranial radiotherapy (CRT) is used to treat a large variety of benign and malignant disorders. We presenttwo cases of late neurological complications after CRT and briefly discuss its diagnosis and their sharedpathophysiological aspects. The first case is a patient with cognitive impairment associated to mineralizing microangiopathy ten years after CRT for nasopharyngeal carcinoma and the second one is a womanwith Stroke-like Migraine Attacks after Radiation Therapy (SMART) syndrome two years after CRT foranaplastic meningioma. Nowadays, higher survival rates might cause an increase in appearance of lateneurological complications after CTR. These reported cases show that late complications can mimic awide variety of neurological conditions and the importance of magnetic resonance image (MRI) to get adiagnosis. (c) 2021 Societe francaise de radiotherapie oncologique (SFRO). Published by Elsevier Masson SAS. Allrights reserved.