Transcriptomic Profiling Identifies an Exosomal microRNA Signature for Predicting Recurrence Following Surgery in Patients With Pancreatic Ductal Adenocarcinoma.

Satoshi Nishiwada,Ya Cui,Masayuki Sho,Eunsung Jun,Takahiro Akahori,Kota Nakamura,Fuminori Sonohara,Suguru Yamada,Tsutomu Fujii,In Woong Han,Susan Tsai,Yasuhiro Kodera,Joon Oh Park,Daniel Von Hoff,Song Cheol Kim,Wei Li,Ajay Goel

Annals of surgery（2022）

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摘要

We identified a novel, noninvasive exo-miRNA signature that robustly predicts recurrence following surgery in patients with PDAC; highlighting its potential clinical impact for optimized patient selection and improved individualized treatment strategies.

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关键词

exosomal miRNAs,neoadjuvant therapy,pancreatic ductal adenocarcinoma,recurrence prediction biomarkers

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