Alcohol consumption preferentially activates a subset of pro-opiomelanocortin (POMC) producing neurons targeting the amygdala
Neuropharmacology(2021)
Abstract
•Female mice consume more alcohol than males during drinking in the dark procedures.•Alcohol consumption activates a subset of POMC neurons within the ArcN.•POMC neurons in the ArcN preferentially target the amygdala over the NAc and VTA.•Alcohol exposure preferentially activates amygdala projecting ArcN POMC neurons.
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Key words
Pro-opiomelanocortin,POMC,Alcohol,FosB,Endogenous opioids,Amygdala
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