Nerve Excitability and Neuropathic Pain is Reduced by BET Protein Inhibition After Spared Nerve Injury

•BET protein inhibition alters pro- and anti-cytokine expression after spared nerve injury.•BET protein inhibition alters ion channel and Na+/K+ pump expression after spared nerve injury.•Nerve excitability and hyperalgesia are reduced by BET protein inhibition after nerve injury.•JQ1 may be used as a pharmacological treatment for neuropathic pain after peripheral nerve lesion.