Safety And Feasibility Of Left Bundle Branch Area Pacing Following Valvular Interventions: Multicenter Study

Objectives To evaluate the safety and feasibility of left bundle branch area pacing (LBBAP) in patients with valvular interventions. Methods Eighty-four patients were included in this study. All patients underwent recent surgical or percutaneous valvular interventions. LBBAP was attempted in all patients. Implant success rates, peri- and postprocedure electrocardiogram, pacing parameters, and complications were assessed at implant, and during follow-up. Results LBBAP implantation was successful in 80/84 (95%) patients. Mean age was 74.1 +/- 13.8 years and 56% patients were male. Prior valvular replacements included: percutaneous aortic (26), surgical aortic (36), combined surgical aortic plus mitral (6), MVR (10), tricuspid (1), and pulmonic (1). Average LVEF was 52.6 +/- 11%. Majority of patients underwent LBBAP due to atrioventricular block (76%) and sinus node disease (13%). Total procedure duration was 74.1 +/- 12.5 min and fluoroscopic duration was 9.7 +/- 6.8 min. Pacing parameters were stable during follow-up period of 10.0 +/- 6.3 months. Pacing QRS duration was significantly narrower than baseline QRS duration (131.5 +/- 31.4 ms vs. 114.3 +/- 13.7 ms, p < .001, respectively). No acute complications were observed. Mean follow-up was 10.0 +/- 6.3 months (median: 8.4 months, min: 1 and max: 24 months). During follow-up, there were three device infections and two patients had loss of LBBA capture within 1 month of implant. Conclusions LBBAP is a feasible and safe pacing modality in patients with prior interventions for valvular heart disease.