Respiratory Pathogen Detection In Children: Saliva As A Diagnostic Specimen

Emma M de Koff,Sjoerd M Euser,Paul Badoux,Judith Sluiter-Post,Dirk Eggink,Elisabeth A M Sanders,Marlies A van Houten

PEDIATRIC INFECTIOUS DISEASE JOURNAL（2021）

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摘要

We compared pathogen detection between saliva, nasopharyngeal and oropharyngeal swabs in children with respiratory symptoms. The sensitivity in nasopharyngeal swabs was 93% (95% confidence interval [CI]: 78%-98%), in oropharyngeal swabs 79% (95% CI: 60%-90%), in saliva overall 76% (95% CI: 58%-88%) and in 18 saliva samples collected with drooling or sponges, 94% (95% CI: 74%-99%). Saliva could be a relevant specimen alternative.

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关键词

respiratory pathogens, saliva, diagnostics, pediatrics

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