Bayesian inference using hierarchical and spatial priors for intravoxel incoherent motion MR imaging in the brain: Analysis of cancer and acute stroke

•Bayesian inference for intravoxel incoherent motion magnetic resonance imaging parameters combining a segmented likelihood with hierarchical and spatial priors.•Performance assessment in realistic numerical brain phantom simulations.•In-vivo mapping of perfusion and diffusion in brains of cancer and acute stroke patients with improved contrast-to-noise ratio.