An adaptive optics module for deep tissue multiphoton imaging in vivo
user-5f3206704c775e3a7964bd8b(2021)
摘要
Understanding complex biological systems requires visualizing structures and processes deep within living organisms. We developed a compact adaptive optics module and incorporated it into two- and three-photon fluorescence microscopes, to measure and correct tissue-induced aberrations. We resolved synaptic structures in deep cortical and subcortical areas of the mouse brain, and demonstrated high-resolution imaging of neuronal structures and somatosensory-evoked calcium responses in the mouse spinal cord at great depths in vivo.
更多查看译文
关键词
Adaptive optics,In vivo,Microscope,Measure (physics),Biomedical engineering,Physics,Deep tissue,Mouse Spinal Cord,Multiphoton imaging
AI 理解论文
溯源树
样例
![](https://originalfileserver.aminer.cn/sys/aminer/pubs/mrt_preview.jpeg)
生成溯源树,研究论文发展脉络
Chat Paper
正在生成论文摘要