Correlation of SARS-CoV-2 Subgenomic RNA with Antigen Detection in Nasal Midturbinate Swab Specimens.

Katherine Immergluck,Mark D. Gonzalez,Jennifer K. Frediani,Joshua M. Levy,Janet Figueroa,Anna Wood,Beverly B. Rogers,Jared O'Neal, Roger Elias-Marcellin,Allie Suessmith,Julie Sullivan,Raymond F. Schinazi,Ahmed Babiker,Anne Piantadosi,Miriam B. Vos,Greg S. Martin,Wilbur A. Lam,Jesse J. Waggoner

EMERGING INFECTIOUS DISEASES（2021）

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摘要

Among symptomatic outpatients, subgenomic RNA of severe acute respiratory syndrome coronavirus 2 in nasal midturbinate swab specimens was concordant with antigen detection but remained detectable in 13 (82.1%) of 16 nasopharyngeal swab specimens from antigen-negative persons. Subgenomic RNA in midturbinate swab specimens might be useful for routine diagnostics to identify active virus replication.

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severe acute respiratory syndrome coronavirus 2,SARS-CoV-2,coronavirus,viruses,coronavirus disease,COVID-19

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