Widespread Pressure Delivered by a Weighted Blanket Reduces Chronic Pain: A Randomized Controlled Trial

•A 15-lb weighted blanket reduced aspects of chronic pain more than a 5-lb weighted blanket.•The heavier weighted blanket was more pain relieving for highly anxious individuals.•Weighted blanket-related pain reductions were not mediated by changes in state anxiety or sleep.•Interoceptive or social-affective effects of deep pressure may mediate pain relief.•A 15-lb weighted blanket may be an accessible, low-cost tool to reduce aspects of chronic pain.