Endophthalmitis After Intravitreal Anti-Vascular Endothelial Factor Injections: Outcomes of Eyes Managed Without Microbiologic Cultures

Samir N Patel,Louis Z Cai,Raziyeh Mahmoudzadeh,Mirataollah Salabati,Tejal Magan,Anthony Obeid,Rebecca R Soares,John W Hinkle,Jason Hsu,James P Dunn,James F Vander,Sunir J Garg

American Journal of Ophthalmology（2022）

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摘要

•Traditional management of endophthalmitis has centered on obtaining microbiologic cultures.•When barriers to acquiring microbiologic specimens exist, eyes may be treated immediately with intravitreal antibiotics.•Eyes managed without microbiologic cultures had similar visual outcomes compared with eye with cultures.•The time critical step of treating endophthalmitis remains immediate treatment with intravitreal antibiotics.

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关键词

Endophthalmitis Vitrectomy Study (EVS),endophthalmitis, intravitreal injection, antibiotics, microbiologic cultures, vitreous cultures, Abbreviations and acronyms, anti-vascular endothelial growth factor inhibitors (anti-VEGF),pars plana vitrectomy (PPV),visual acuity (VA)

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