Toward 100 ps Coincidence Time Resolution Using Multiple Timestamps in Depth-Encoding PET Modules: A Monte Carlo Simulation Study

Coincidence time resolution (CTR) in modern time-of-flight (TOF) PET scanners is limited by properties of the detector system, namely scintillator size and material, as well as single-photon time resolution (SPTR) and photon detection efficiency of the readout pixels. Recent studies have demonstrated the effectiveness of incorporating depth of interaction (DOI) information into TOF readout to impr...