YAP1 protein expression has variant prognostic significance in small cell lung cancer (SCLC) stratified by histological subtypes

Lung Cancer(2021)

引用 8|浏览30
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摘要
•C-SCLC has higher level of YAP1 protein expression than P-SCLC.•YAP1 expression was associated worse OS for C-SCLC, but not prognostic for P-SCLC.•The small cell components of P-SCLC and C-SCLC were of different entities.•Positive YAP1 expression might be an actionable target for C-SCLC patients.
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关键词
Yes-associated protein 1 (YAP1),Small cell lung cancer (SCLC),Combined SCLC (C-SCLC),Prognosis,Biomarker
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