Neurodevelopmental malformations of the cerebellum and neocortex in the Shank3 and Cntnap2 mouse models of autism

Gonzalo H Otazu,Yan Li,Zachary Lodato, Adel Elnasher,Katherine M Keever,Ying Li,Raddy L Ramos

Neuroscience Letters（2021）

引用 5|浏览3

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摘要

•Cntnap2 and Shank3 mice exhibit neocortical and cerebellar malformations.•Malformations are characterized by glio-neuronal heterotopia.•Malformations in Cntnap2 and Shank3 mice are due to the C57BL/6 background.

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关键词

Heterotopia,Mouse models,C57BL/6,Shank3,Cntnap2,Neuronal migration

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