Next-Generation Sequencing-Directed Therapy in Patients with Metastatic Breast Cancer in Routine Clinical Practice.

Simona Bruzas,Sherko Kuemmel,Hakima Harrach,Elisabeth Breit,Beyhan Ataseven,Alexander Traut, Anna Rüland,Athina Kostara,Ouafaa Chiari,Christine Dittmer-Grabowski,Mattea Reinisch

CANCERS（2021）

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摘要

Next-generation sequencing (NGS) followed by matched therapy has opened up new therapeutic options to patients with metastatic breast cancer (mBC). Here we report our experience with this approach in everyday clinical practice. This retrospective study included 95 patients with mBC who were genotyped with the FoundationOne ®nn

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关键词

breast cancer, metastatic, next-generation sequencing, NGS, molecular profiling, targeted therapy, precision medicine

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