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Cross-sectional Study on the Proportion of Smell and Taste Disturbances in Hospitalized COVID-19 Patients

Niken Lestari Poerbonegoro,Mirta Hediyati Reksodiputro, Dewi Puspito Sari, Thalia Mufida, Muhammad Ade Rahman, Lupita Adina Reksodiputro,Sacha Audindra,Mikhael Yosia

Annals of medicine and surgery(2021)

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摘要
BACKGROUND:The number of confirmed Coronavirus Disease-2019 (COVID-19) cases in Indonesia had reached 1.4 million cases from a total population of 270 million. Smell and/or taste disturbances are frequently found as early symptoms of COVID-19 patients. Our study aimed to investigate the proportion and characteristics of anosmia and/or ageusia in COVID-19.MATERIALS AND METHODS:This cross-sectional study identifies the proportion and severity of smell and taste disturbances in COVID-19 patients. Subjects were recruited by consecutive sampling. All subjects were required to fill in the questionnaire modified from the American Academy of Otolaryngology-Head and Neck Surgery Anosmia Reporting Tool (AAO-HNS ART). Symptoms severity was measured with a numerical rating scale of 0-10; 0-3 is defined as mild, 4-6 as moderate, and 7-10 as severe.RESULTS:Out of 51 subjects, 34 (66.7%) suffered from smell and/or taste disturbances. Twenty-nine of 34 subjects (85.3%) suffered from smell disturbance, and 24 of 34 subjects (70.5%) suffered from taste disturbance. Severe smell disturbance occurred in 68.9% of subjects, while severe taste disturbance occurred in 50%. The median onset was three days for smell disturbance and four days for taste disturbance after any symptoms of COVID-19.CONCLUSION:Smell and/or taste disturbances were early symptoms of COVID-19. These symptoms commonly occurred within the first four days of clinical onset and frequently manifested in severe conditions.
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关键词
Anosmia,Ageusia,COVID-19,Indonesia
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