Neonatal blockade of NR2A-containing but not NR2B-containing NMDA receptor induces spatial working memory deficits in adult rats
Neuroscience Research（2022）
摘要
•Neonatal NMDA receptor blockade causes behavioral abnormalities in adulthood.•PEAQX-treated and MK-801-treated rats showed spatial working memory deficits.•Ifenprodil-treated rats did not show any behavioral changes.•NR2A-containing NMDA receptor is indispensable for proper brain development in rats.
更多查看译文
关键词
N-methyl-d-aspartate receptor,Chronic postnatal treatment,NR2 subunit,Spatial working memory,Schizophrenia,Rat
AI 理解论文
溯源树
样例
生成溯源树，研究论文发展脉络
Chat Paper
正在生成论文摘要