Nanoengineered Shear-Thinning Hydrogel Barrier for Preventing Postoperative Abdominal Adhesions

Guillermo U. Ruiz-Esparza,Xichi Wang,Xingcai Zhang, Sofia Jimenez-Vazquez, Liliana Diaz-Gomez, Anne-Marie Lavoie,Samson Afewerki,Andres A. Fuentes-Baldemar,Roberto Parra-Saldivar,Nan Jiang,Nasim Annabi,Bahram Saleh,Ali K. Yetisen,Amir Sheikhi,Thomas H. Jozefiak,Su Ryon Shin,Nianguo Dong,Ali Khademhosseini

Nano-Micro Letters（2021）

引用 26|浏览18

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摘要

Highlights A novel “nanoengineered hydrogel” barrier based on silicate nanoplatelets and poly(ethylene oxide) (PEO) was developed to prevent the formation of postoperative adhesions. Compared to other hydrogel systems, the prepared biomaterial is injectable and sprayable which makes it compatible with minimally invasive interventions.

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关键词

Postoperative adhesions,Shear-thinning hydrogel,Silicate nanoplatelets,Nanotechnology,Nanomedicine

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