The natural history of 21-hydroxylase autoantibodies in autoimmune Addison's disease.

Anette Boe Wolff,Lars Breivik,Karl Ove Hufthammer,Marianne Aardal Grytaas,Eirik Bratland,Eystein Sverre Husebye,Bergithe Eikeland Oftedal

European journal of endocrinology（2021）

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摘要

21OH-autoantibodies are reliable and robust markers for autoimmune Addison's disease, linked to HLA risk genotype. However, a negative test in patients with long disease duration does not exclude autoimmune aetiology.

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