Genetic variants predictive of chemotherapy-induced peripheral neuropathy symptoms in gynecologic cancer survivors

Gynecologic Oncology(2021)

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摘要
•Chemotherapy induced peripheral neuropathy is a common treatment-related side effect and associated with genetic variants.•2 SNPs were associated with neuropathy symptoms in non-Hispanic white gynecologic cancer patients treated with chemotherapy.•Combining significant SNPs with clinical risk factors resulted in a superior predictive model of neuropathy symptoms.
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关键词
Neuropathy,Chemotherapy,Gynecologic cancer survivors,Chemotherapy induced peripheral neuropathy,Gynecologic cancer
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