Second compartment widens plasmid invasion conditions: Two-compartment pair-formation model of conjugation in the gut

Jesse B. Alderliesten,Mark P. Zwart,J. Arjan G.M. de Visser,Arjan Stegeman,Egil A.J. Fischer

Journal of Theoretical Biology（2022）

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摘要

•Conditions at the gut wall affect plasmid invasion dynamics in the entire gut.•Bulk-conjugation models capture pair-formation dynamics well.•Experimental data on transconjugant characteristics important to parameterize model.

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关键词

Plasmid dynamics,Mating pair,Horizontal gene transfer,Mathematical modelling,Mucosal environment

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