Perioperative Management of Psychiatric and Neurological Long-Term Medication

More than a third of all patients undergoing surgery take psychotropic agents on a regular basis. Aside from classical indications like depression and psychosis these drugs are often prescribed for treatment of pain, anxiety and panic disorder. Over the last 30 years the frequency of prescription of psychotropic drugs increased by seven times. Of note, drug interactions of psychoactive medications and anaesthetic agents are common, and the therapeutic range is narrow. Since not all of these agents can be stopped uncritically, careful assessment of risks and benefits is obligatory. The anaesthesiologist has to take special care or avoid the use of certain medications.Medical treatment is crucial for the treatment of several neurological disorders. Frequently, anaesthesiologists are faced with common diseases like seizure disorders, Parkinson's disease and Myasthenia gravis. Perioperative withdrawal of specific medication implies the risk of recurrence of the neurological symptoms. Therefore, these drugs should be continued postoperatively as soon as possible.