Identifying the beta-site amyloid precursor protein cleaving enzyme 1 interactome through the proximity-dependent biotin identification assay

Jennie L. Gabriel,Michele Tinti,William Fuller,Michael L.J. Ashford

Neuroscience Letters（2022）

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摘要

•Biotin identification proximity assay used to determine BACE1 interactome.•Insight into BACE1 trafficking and protein interactions independent of proteolysis.•Identified progesterone receptor component 2 as a novel BACE1 protein partner.

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关键词

BACE1,APP,PGRC2,Aβ

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