Comparative evaluation of T-cell receptors in experimental glioma-draining lymph nodes.

Jens Blobner,Michael Kilian,Chin Leng Tan,Katrin Aslan,Khwab Sanghvi,Jochen Meyer,Manuel Fischer, Kristine Jähne,Michael O Breckwoldt,Felix Sahm,Andreas von Deimling,Martin Bendszus,Wolfgang Wick,Michael Platten,Edward Green,Lukas Bunse

Neuro-oncology advances（2021）

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摘要

In experimental glioblastoma, our data did not provide evidence that glioma-draining cervical lymph nodes are a robust reservoir for spontaneous glioma-specific T cells highlighting the requirement for detailed analyses of glioma-infiltrating T cells for the discovery of tumor-specific TCR.

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关键词

TCR discovery,glioblastoma,glioma draining lymph nodes

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