Effect of Bloodletting at Shaoshang and Shangyang Acupuncture Points on Outcome and Prognosis of Severe Community-Acquired Pneumonia in the Elderly

Yuefeng Fu, Zhe Yang,Yangping Cai, Hongshuan Liu,Shuo Li, Nan Kou,Jingqin Wu,Qing Zhang

DISEASE MARKERS(2021)

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摘要
Objectives. The aim of this study was to explore, whether treatment with bloodletting at Shaoshang and Shangyang acupuncture points would affect therapy outcome and prognosis for severe community-acquired pneumonia (SCAP) in the elderly. Methods. A total of 62 patients, who met the diagnostic criteria for SCAP, were enrolled in the study and randomly divided into two groups, i.e., treatment group (n=31) and control group (n=31). All patients received a therapy according to the Chinese Clinical Practice and Expert Consensus of Emergency Severe Pneumonia from 2016. In addition to that, a bloodletting at Shaoshang (LU11) and Shangyang (LI1) acupuncture points was applied for the treatment group. This intervention was repeated for three times (ones daily), bloodletting a volume of 2-3 ml at each time point. Differences in a main index of clinical efficacy, body temperature (T), respiratory rate (RR), heart rate (Hr), white blood cell count (WBC), neutrophil percentage (N%), and C-reactive protein level (CRP) as well as different scores (CURB-65 score, SOFA score, and Apache II score) were compared between groups. Moreover, the 28-day mortality was compared between treatment and control group. The statistical methods involved in carrying out the current study include t-test, Wilcoxon test, and chi-square test. Results. The clinical effective rate of the treatment group was 82.9%, which was significantly higher than the 17.1% in the control group (P<0.05). After finishing the intervention, the treatment group showed significantly lower T (37.28 +/- 0.54 vs. 37.82 +/- 0.81), RR (20.06 +/- 2.67 vs. 23.71 +/- 6.85), Hr (81.71 +/- 10.38 vs. 93.84 +/- 15.39), CUBR-65 score (2.16 +/- 0.74 vs. 3.03 +/- 0.98), and SOFA score (5.84 +/- 3.83 vs. 8.16 +/- 4.2) compared to the control group (P<0.05). The 28-day mortality rate of the treatment group was significantly lower than in the control group (12.9% vs. 45.2%, P=0.05). Conclusions. Bloodletting at Shaoshang and Shangyang acupuncture points can support improving the clinical treatment efficacy for SCAP and reduce the 28-day mortality rate in the elderly.
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