Agrin Loss in Barrett's Esophagus-Related Neoplasia and Its Utility as a Diagnostic and Predictive Biomarker.

Steffen Rickelt,Azfar Neyaz,Charlene Condon,Charles A Whittaker,Ali H Zaidi,Martin S Taylor,Genevieve Abbruzzese,Anthony R Mattia,Lawrence Zukerberg,Stuti G Shroff,Omer H Yilmaz,Osman Yilmaz,Elizabeth Y Wu,Won-Tak Choi,Blair A Jobe,Robert D Odze,Deepa T Patil,Vikram Deshpande,Richard O Hynes

Clinical cancer research : an official journal of the American Association for Cancer Research（2022）

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摘要

We highlight ECM changes during Barrett's esophagus progression to neoplasia. BM AGRN loss is a novel diagnostic biomarker that can identify patients with NDBE at increased risk of developing advanced neoplasia.

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