Species and strain cultivation of skin, oral, and gut microbiota
biorxiv(2021)
摘要
Genomics-driven discovery of microbial species have provided extraordinary insights into the biodiversity of human microbiota. High resolution genomics to investigate species- and strain-level diversity and mechanistic studies, however, rely on the availability of individual microbes from a complex microbial consortia. Here, we describe and validate a streamlined workflow for cultivating microbes from the skin, oral, and gut microbiota, informed by metagenomic sequencing, mass spectrometry, and strain profiling.
### Competing Interest Statement
The authors have declared no competing interest.
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关键词
gut microbiota,cultivation,strain,species,skin
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