Treatment With Sq1274, A Novel Tubulin Polymerization Inhibitor, Results In Improved Therapeutic Efficacy Compared To Paclitaxel In Serous Gynecologic Cancers

K. A. Mills,S. T. Roach,J. M. Quinn,C. M. Starks, A. R. Ilivicky,A. R. Hagemann,C. K. Mccourt,P. H. Thaker,M. A. Powell,D. G. Mutch,K. C. Fuh

GYNECOLOGIC ONCOLOGY（2018）

引用 0|浏览8

暂无评分

摘要

Objective: To determine whether SQ1274, a novel tubulin polymerization inhibitor, is a more effective chemotherapeutic agent than paclitaxel; examine whether this inhibitor downregulates the receptor tyrosine kinase, AXL (an active pathway in ovarian and uterine cancer metastasis); and evaluate the therapeutic potential of SQ1274 in a xenograft mouse model.

查看译文

关键词

novel tubulin polymerization inhibitor,paclitaxel,cancers,therapeutic efficacy

AI 理解论文

溯源树

样例

生成溯源树，研究论文发展脉络

Chat Paper

正在生成论文摘要