Blood Glucose And Alanine Transaminase Lowering Effect Of Nepeta Cataria L. In Alloxan Monohydrate Induced Diabetic Rabbits

Diabetes mellitus is has become world most dangerous disease which needs attention as soon as possible. Hyperglycemia in blood badly affects different organs like eyes, kidneys, nerves and human circulatory system. Anti-diabetic capability of Nepeta Cateria has been investigated in rabbit. Group A, worked as normal control, and Group B remain Diabetic control. This group was interacted or treated by Glucophage with a dose rate of 8 mg /kg weight and for comparison with the other groups which were kept on feeding N. cateria extract as a treatment. Group C, D and E were given with plant extract at the quantity of 120 mg /kg, 220 mg /kg and 320 mg /kg of its body weight respectively. The blood samples were composed of all the groups by particular schedule i.e. two hours, four hours, six hours and eight hours concurrently. In every of two hours' sample of blood was collected with particular fashion, serum detached and level of glucose and ALT level was examined by the kit method and found that ALT level reduced to 54 IU/L. The result showed that treatment of 320 mg/kg dose is effective lowering blood glucose up to 159.33 mg/Kg and ALT in the experimental animal. The data obtained disclose that N. cateria ethanol extract reduced the glucose level. So, it is determined that the N. cateria possess major diabetic compressed activity.