A Novel Approach For Malaria Treatment

INTERNATIONAL JOURNAL OF ADVANCED BIOTECHNOLOGY AND RESEARCH(2015)

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摘要
Malaria eradication is still away from reach due to the development of multiple drug resistance and the side effects associated with the use of conventional antimalarial chemotherapy. Developing novel approaches to administer these derivatives by some alternative parenteral route would be valuable in overcoming their therapeutic limitations. Nanotechnology has the potential to improve the safety and efficacy of drug delivery and help the cause of malaria eradication. Many of the problems associated with conventional dosage forms and delivery systems such as poor bioavailability, non-specificity, rapid metabolism and excretion amongst others can be solved through pharmaceutical nanotechnology. This review highlights on the novel approaches such as lipid and polymeric nanoparticles in drug delivery for the treatment of malaria.
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关键词
anti-malarial, nanotechnology, drug delivery, lipid nanoparticles, polymeric nanoparticles
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